Valtrex Drug Interactions

Valtrex drug interactions with other medications, such as cimetidine, probenecid, and tenofovir, can increase the level of Valtrex in your blood. In most cases, this will not cause problems and the doses will not need to be adjusted. However, your risk of side effects due to these Valtrex drug interactions are increased if you have poor kidney function. Therefore, your healthcare provider may adjust your doses if this is the case for you.

Valtrex Medication

An Overview of Valtrex Drug Interactions

Valtrex^® (valacyclovir hydrochloride) can potentially interact with many drugs. Some of the drugs that may lead to Valtrex drug interactions include:

Cimetidine (Tagamet^®)
Probenecid (Benuryl^®, Benemid^®, ColBenemid^®)
Tenofovir (Viread^®).

More Information on Valtrex Interactions

The following sections explain in detail how certain drugs can interact in a negative fashion when taken with Valtrex.

Cimetidine

Taking Valtrex with cimetidine can increase the level of Valtrex in your blood. For most people, this interaction will not cause any problems, and the doses of these medications do not need to be adjusted. However, your risk of side effects due to this interaction is increased if you have poor kidney function. Talk to your healthcare provider about combining these medications if you have kidney problems.

Probenecid

Taking Valtrex and probenecid together can increase the level of Valtrex in your blood. For most people, this interaction will not cause any problems, and the doses of these medications do not need to be adjusted. However, your risk of side effects due to this interaction is increased if you have poor kidney function. If you have kidney problems, talk to your healthcare provider about combining these medications.

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