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Understanding How Xerese Works and Specific Uses

How Does Xerese Work?

As mentioned, Xerese is a combination of acyclovir and hydrocortisone. Acyclovir is an antiviral medication. It prevents the virus that causes cold sores (herpes simplex virus, or HSV) from multiplying. Hydrocortisone is a corticosteroid medication. It reduces inflammation, which can help relieve pain, swelling, redness, and itching.
 
Unlike most viruses, HSV is never completely removed from the body. Instead, it remains inactive in certain nerve cells, waiting to become active again. This is the reason cold sores come back. Xerese is not a cure for cold sores. It also will not prevent future cold sores from occurring.
 

Can Older Adults Use It?

Yes, older adults can use Xerese. Clinical studies did not include enough older adults to say for certain that the medication is safe and effective in this group. However, at this time, older adults are expected to respond to it no differently than other age groups.
 

Can Children Use Xerese?

Xerese is approved for use in adolescents as young as 12 years old. Talk with your child's healthcare provider about the benefits and risks.
 

Is Xerese Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this product for something other than cold sores. At this time, there are no well-accepted off-label uses for Xerese.
 

Xerese Drug Information

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