Available by prescription only, Xerese is a medication used for the treatment of cold sores. It comes in the form of a cream that is applied to the affected area five times a day for five days. Possible side effects include redness and dry or flaky skin. Although it can speed up the healing time of a cold sore, it cannot prevent future cold sores.
Xerese™ (acyclovir and hydrocortisone) is a prescription medication approved to treat cold sores. It is a combination of two medicines: acyclovir and hydrocortisone. Xerese comes in the form of a cream.
How Does It Work?As mentioned, Xerese is a combination of acyclovir and hydrocortisone. Acyclovir is an antiviral medication. It prevents the virus that causes cold sores (herpes simplex virus, or HSV) from multiplying. Hydrocortisone is a corticosteroid medication. It reduces inflammation, which can help relieve pain, swelling, redness, and itching.
Unlike most viruses, HSV is never completely removed from the body. Instead, it remains inactive in certain nerve cells, waiting to become active again. This is the reason cold sores come back. Xerese is not a cure for cold sores. It also will not prevent future outbreaks.